Propositional attitudes are often classified as non-phenomenal mental states. I argue that there is no good reason for doing so. The unwillingness to view propositional attitudes as being essentially phenomenal stems from a biased notion of phenomenality, from not paying sufficient attention to the idioms in which propositional attitudes are usually reported, from overlooking the considerable degree to which different intentional modes can be said to be phenomenologically continuous, and from not considering the possibility that propositional attitudes may be transparent, (...) just like sensations and emotions are commonly held to be: there may be no appropriate way of describing their phenomenal character apart from describing the properties and objects they represent. (shrink)

BACKGROUND -/- The need for detailed description and modeling of cells drives the continuous generation of large and diverse datasets. Unfortunately, there exists no systematic and comprehensive way to organize these datasets and their information. CELDA (Cell: Expression, Localization, Development, Anatomy) is a novel ontology for the association of primary experimental data and derived knowledge to various types of cells of organisms. -/- RESULTS -/- CELDA is a structure that can help to categorize cell types based on species, anatomical localization, (...) subcellular structures, developmental stages and origin. It targets cells in vitro as well as in vivo. Instead of developing a novel ontology from scratch, we carefully designed CELDA in such a way that existing ontologies were integrated as much as possible, and only minimal extensions were performed to cover those classes and areas not present in any existing model. Currently, ten existing ontologies and models are linked to CELDA through the top-level ontology BioTop. Together with 15.439 newly created classes, CELDA contains more than 196.000 classes and 233.670 relationship axioms. CELDA is primarily used as a representational framework for modeling, analyzing and comparing cells within and across species in CellFinder, a web based data repository on cells (http://cellfinder.org). -/- CONCLUSIONS -/- CELDA can semantically link diverse types of information about cell types. It has been integrated within the research platform CellFinder, where it exemplarily relates cell types from liver and kidney during development on the one hand and anatomical locations in humans on the other, integrating information on all spatial and temporal stages. CELDA is available from the CellFinder website: http://cellfinder.org/about/ontology. (shrink)

This title opens the debate about what an ethics for the 21st century would look like and the role of corporations and how to work to ensure they produce results which benefit society as a whole.

IN Physics VIII, 10, Aristotle seems to commit a serious mistake: just before concluding that the first mover required by all motion everywhere remains invariable and without parts or magnitude, Aristotle apparently locates this mover on the circumference of the cosmos.

The computations involved in statistical learning have long been debated. Here, we build on work suggesting that a basic memory process, chunking, may account for the processing of statistical regularities into larger units. Drawing on methods from the memory literature, we developed a novel paradigm to test statistical learning by leveraging a robust phenomenon observed in serial recall tasks: that short‐term memory is fundamentally shaped by long‐term distributional learning. In the statistically induced chunking recall (SICR) task, participants are exposed to (...) an artificial language, using a standard statistical learning exposure phase. Afterward, they recall strings of syllables that either follow the statistics of the artificial language or comprise the same syllables presented in a random order. We hypothesized that if individuals had chunked the artificial language into word‐like units, then the statistically structured items would be more accurately recalled relative to the random controls. Our results demonstrate that SICR effectively captures learning in both the auditory and visual modalities, with participants displaying significantly improved recall of the statistically structured items, and even recall specific trigram chunks from the input. SICR also exhibits greater test–retest reliability in the auditory modality and sensitivity to individual differences in both modalities than the standard two‐alternative forced‐choice task. These results thereby provide key empirical support to the chunking account of statistical learning and contribute a valuable new tool to the literature. (shrink)

It is shown that the Born Rule probabilities, i.e. the squares of the moduli of the coefficients in a pure state superposition, refer to mutually exclusive events consequent on measurement. It is also shown that the eigenstates in a pure state superposition are not mutually exclusive events. If the Born Rule is to be retained as the fundamental interpretative postulate of quantum mechanics then it follows, firstly, that the probabilities necessarily refer not to the eigenstates but to the eigenvalues to (...) which the eigenstates belong and, secondly, that the eigenvalues are necessarily mutually exclusive events. This means that to ask why a measurement of an observable on a system in a pure state superposition of eigenstates yields a single state rather than all the states in the superposition is to ill-pose the quantum measurement problem. The events the Born Rule probabilities properly refer to are not states but values. And it also means that the correctly-posed measurement problem, why does a measurement of an observable in a pure state superposition of the eigenstates of the observable yield a single eigenvalue rather than all the eigenvalues implicit in the superposition, admits of the answer: the values, being mutually exclusive events, constitute a statistical mixture of values, and as such, a measurement will yield just one of them. (shrink)

The sequencing of the human genome and decreasing costs of sequencing technology have led to the notion of ‘personalized medicine’. This has been taken by some authors to indicate that personalized medicine will provide individualized treatments solely based on one’s DNA sequence. We argue this is overly optimistic and misconstrues the notion of personalization. Such interpretations fail to account for economic, policy and structural constraints on the delivery of healthcare. Furthermore, notions of individualization based on genomic data potentially take us (...) down the road of genetic reductionism obscuring the role of environmental factors in disease and ill health. We propose that one should see personalized medicine as a way of using personal genomic information to stratify individuals into subpopulations and suggest that personalized medicine be seen within a broader idea of personalized healthcare, reflecting healthcare that integrates personal genomic data into cultural, environmental and personal contexts. (shrink)

The essay published here in English was one of the earliest documents of the birth of the form of idealism which Giovanni Gentile called “Actual Idealism.” The most celebrated full-length statement of it was published in 1916 as General Theory of the Spirit as Pure Act. But there is no other essay in which the relation between Gentile’s view and the great German tradition from which it derives is made so plain.

Many have argued against the claim that Plato posited the mathematical objects that are the subjects of Metaphysics M and N. This paper shifts the burden of proof onto these objectors to show that Plato did not posit these entities. It does so by making two claims: first, that Plato should posit the mathematical Intermediates because Forms and physical objects are ill suited in comparison to Intermediates to serve as the objects of mathematics; second, that their utility, combined with Aristotle’s (...) commentary on Plato’s posit of Intermediates, provides good reason to conclude that Plato did posit them. (shrink)